Liposomes, The Attractive Vehicles for Drug Delivery: A Scientometric Mapping of Web of Science Indexed Literature

Dandoti, Sayequa Shujauddin; Ansari, Khadeeja MN; Rahaman, Md Safiqur

doi:10.22034/ijism.2023.1977948.0

Document Type : Articles

Authors

¹ Lecturer, Department of Basic Sciences, Deanship of Preparatory Year and Supporting Studies, Imam Abdulrahman Bin Faisal University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

² Lecturer, Interior Design Department, College of Design, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

³ Librarian, Deanship of Library Affairs, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.

https://doi.org/10.22034/ijism.2023.1977948.0

Abstract

The Liposome is a spherical-shaped vesicle composed of one or more phospholipid bilayers, closely resembling cell membranes' structure. It has a novel drug delivery system (NDDS); the lipid bilayer can fuse with other bilayers, such as the cell membrane, thus delivering the liposome contents. The present study has been conducted to map the research productivity of 'liposomes as drug delivery' between 1980 and 2021. This study employed the scientometric method to analyze 629 research papers indexed in the Web of Science database. Different bibliometrics indicators were used to assess the annual research growth, prolific authors, authorship pattern, funding agencies, productive source, organization, country, author keywords, cited paper and cited references, etc. Biblioshiny, Bibexcel, VOSviewer, and MS Office were used to analyze the 629 published papers. The findings show that 629 publications were published between 1980 and 2001, with 24674 citations. 2018 and 2019 recorded the highest research with 49 publications and 758 and 471 citations, respectively. Journal of Controlled Release was the most relevant source in the field, with 45 publications and 3063 citations. LIU Y was the most productive author, with 15 publications and 342 citations. Northwestern University USA has the highest record with 11 publications, and the USA was the most productive country with 181 publications, while China emerged as a leading collaborator with the USA (19 publications). Liposomes and cationic liposomes were identified as the most important research themes. Permeability, ocular drug delivery, Chemotherapy, Cancer therapy, Hypoxia, Combination therapy, and hyaluronic acid were research topics that had gained recent popularity. At the same time, Vesicles targeted drug delivery, cellular uptake, ultrasound, Chitosan, and Pegylation were identified as the research areas that require further attention in the field of liposomes as drug delivery research.

Keywords

20.1001.1.20088302.2023.21.4.16.2

References

Al-Jamal, W. T. & Kostarelos, K. (2011). Liposomes: From a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine. Accounts of Chemical Research, 44(10), 1094-1104. https://doi.org/10.1021/ar200105p

Ale Ebrahim, S., Zamani Pedram, M., Ale Ebrahim, N. (2020). Current Status of Systemic Drug Delivery Research: A Bibliometric Study. In: Lai, WF. (Ed.) systemic delivery technologies in Anti-Aging Medicine: Methods and Applications. Healthy Ageing and Longevity, vol 13. Springer, Cham. https://doi.org/10.1007/978-3-030-54490-4_2

Allen, T. M. (1994). Long-circulating (sterically stabilized) liposomes for targeted drug delivery. Trends in Pharmacological Sciences, 15(7), 215-220. https://doi.org/10.1016/0165-6147(94)90314-x

Allen, Theresa M & Cullis, P. R. (2013). Liposomal drug delivery systems: From concept to clinical applications. Advanced Drug Delivery Reviews, 65(1), 36-48. https://doi.org/10.1016/j.addr.2012.09.037

Allison, A. C. & Gregoriadis, G. (1974). Liposomes as immunological adjuvants. Nature, 252(5480), 252-252. https://doi.org/10.1038/252252a0

Ansari, K. M. N., Khan, N. B. N., Omar, N. F. B. M., El-Wakeel, H. A. & Rahaman, M. S. (2021). Assessment of literature growth in Anthropometric measurement research : A bibliometric analyses of Scopus indexed publications. Library Philosophy and Practice (e-journal). 5901. https://digitalcommons.unl.edu/libphilprac/5901

Bangham, A. D. (1993). Liposomes: The Babraham connection. Chemistry and Physics of Lipids, 64(1-3), 275-285. https://doi.org/10.1016/0009-3084(93)90071-A

Bangham, A. D. & Horne, R. W. (1964). Negative staining of phospholipids and their structural modification by surface-active agents as observed in the electron microscope. Journal of Molecular Biology, 8, 660-668. http://dx.doi.org/10.1016/S0022-2836(64)80115-7

Bangham, A. D., Standish, M. M. & Watkins, J. C. (1965). Diffusion of univalent ions across the lamellae of swollen phospholipids. Journal of Molecular Biology, 13(1), 238-252. https://doi.org/https://doi.org/10.1016/S0022-2836(65)80093-6

Barenholz, Y. (2012). Doxil®--the first FDA-approved nano-drug: Lessons learned. Journal of Controlled Release : Official Journal of the Controlled Release Society, 160(2), 117-134. https://doi.org/10.1016/j.jconrel.2012.03.020

Bobo, D., Robinson, K. J., Islam, J., Thurecht, K. J. & Corrie, S. R. (2016). Nanoparticle-based medicines: A review of FDA-approved materials and clinical trials to. Pharmaceutical Research, 33(10), 2373-87. http://dx.doi.org/10.1007/s11095-016-1958-5

Bozzuto, G. & Molinari, A. (2015). Liposomes as nanomedical devices. International Journal of Nanomedicine, 10, 975-999. https://doi.org/10.2147/IJN.S68861

Daraee, H., Etemadi, A., Kouhi, M., Alimirzalu, S. & Akbarzadeh, A. (2016). Application of liposomes in medicine and drug delivery. Artificial Cells, Nanomedicine, and Biotechnology, 44(1), 381-391. https://doi.org/10.3109/21691401.2014.953633

Dromi, S., Frenkel, V., Luk, A., Traughber, B., Angstadt, M., Bur, M., Poff, J., Xie, J., Libutti, S. K., Li, K. C. P. & Wood, B. J. (2007). Pulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effect. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 13(9), 2722-2727. https://doi.org/10.1158/1078-0432.CCR-06-2443

Drummond, D. C., Meyer, O., Hong, K., Kirpotin, D. B. & Papahadjopoulos, D. (1999). Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacological Reviews, 51(4), 691-743.

Drummond, D. C., Zignani, M. & Leroux, J. (2000). Current status of pH-sensitive liposomes in drug delivery. Progress in Lipid Research, 39(5), 409-460. https://doi.org/10.1016/s0163-7827(00)00011-4

El Maghraby, G. M., Barry, B. W. & Williams, A. C. (2008). Liposomes and skin: from drug delivery to model membranes. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 34(4-5), 203-222. https://doi.org/10.1016/j.ejps.2008.05.002

Gregoriadis, G. (1995). Engineering liposomes for drug delivery: Progress and problems. Trends in Biotechnology, 13(12), 527-537. https://doi.org/10.1016/S0167-7799(00)89017-4

Gregoriadis, G. & Perrie, Y. (2010). Liposomes. In Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd:Chichester. https://doi.org/10.1002/9780470015902.a0002656.pu

He, H., Lu, Y., Qi, J., Zhu, Q., Chen, Z. & Wu, W. (2019). Adapting liposomes for oral drug delivery. Acta pharmaceutica sinica B, 9(1), 36-48. https://doi.org/10.1016/j.apsb.2018.06.005

Klibanov, A. L., Maruyama, K., Torchilin, V. P. & Huang, L. (1990). Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Letters, 268(1), 235-237. https://doi.org/10.1016/0014-5793(90)81016-h

Li, L., Hou, J., Liu, X., Guo, Y., Wu, Y., Zhang, L. & Yang, Z. (2014). Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas. Biomaterials, 35(12), 3840–3850. https://doi.org/10.1016/j.biomaterials.2014.01.019

Malam, Y., Loizidou, M. & Seifalian, A. M. (2009). Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer. Trends in Pharmacological Sciences, 30(11), 592-599. https://doi.org/10.1016/j.tips.2009.08.004

Mayhew, E., Lazo, R., Vail, W. J., King, J. & Green, A. M. (1984). Characterization of liposomes prepared using a microemulsifier. Biochimica et Biophysica Acta (BBA)-Biomembranes, 775(2), 169-174. https://doi.org/10.1016/0005-2736(84)90167-6

Mezei, M. & Gulasekharam, V. (1980). Liposomes - A selective drug delivery system for the topical route of administration. Lotion dosage form. Life Sciences, 26(18), 1473-1477. https://doi.org/10.1016/0024-3205(80)90268-4

Needham, D., Anyarambhatla, G., Kong, G. & Dewhirst, M. W. (2000). A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. Cancer Research, 60(5), 1197-1201. https://doi.org/ 10.3390/pharmaceutics15071886

Papahadjopoulos, D., Allen, T. M., Gabizon, A., Mayhew, E., Matthay, K., Huang, S. K., Lee, K. D., Woodle, M. C., Lasic, D. D. & Redemann, C. (1991). Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proceedings of the National Academy of Sciences of the United States of America, 88(24), 11460-11464. https://doi.org/10.1073/pnas.88.24.11460

Persson, O., Danell, R. & Schneider, J. W. (2009). How to use Bibexcel for various types of bibliometric analysis. In Celebrating scholarly communication studies: A Festschrift for Olle Persson at his 60th Birthday (pp. 9-24). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25636

Rahaman, M. S., Ansari, K. M., Kumar, H. & Shah, K. (2022). Mapping and visualizing research output on global solid waste management: a bibliometric review of literature. Science & Technology Libraries, 41(2), 174-202. https://doi.org/10.1080/0194262X.2021.1960943

Rahaman, S., Kumar, S., Ansari, K. M. N. & Rahman, R. (2021). Twenty-five years of global research publications trends of novel coronavirus: A scientometrics assessment. Library Philosophy and Practice (e-journal). 4294. https://digitalcommons.unl.edu/libphilprac/4294

Rahaman, M. S., Kumar, S. & Shah, K. (2021). A scientometric assessment of global research productivity in traditional knowledge:Evidence from scopus database. Kelpro Bulletin, 25(1), 15-29. Retrieved from

Rendi, R. (1965). Sodium, potassium-requiring adenosinetriphosphatase activity II. mechanism of inhibition by sulphydryl reagents. Biochimica et Biophysica Acta (BBA)-Enzymology and Biological Oxidation, 99(3), 564-566. https://doi.org/10.1016/S0926-6593(65)80215-6

Robert, C., Wilson, C. S., Venuta, A., Ferrari, M. & Arreto, C. D. (2017). Evolution of the scientific literature on drug delivery: A 1974-2015 bibliometric study. Journal of Controlled Release, 260, 226-233. https://doi.org/10.1016/j.jconrel.2017.06.012

Schreier, H. & Bouwstra, J. (1994). Liposomes and niosomes as topical drug carriers: dermal and transdermal drug delivery. Journal of Controlled Release, 30(1), 1-15. https://doi.org/https://doi.org/10.1016/0168-3659(94)90039-6

Sharma, A. K. (2021). Scientometric Analysis of Global Publication Output in Liposome Research (2011-2020). Library Philosophy and Practice (e-journal). 5301. Retrieved from https://digitalcommons.unl.edu/libphilprac/5301

Sharma, A., & Sharma, U. S. (1997). Liposomes in drug delivery: Progress and limitations. International Journal of Pharmaceutics, 154(2), 123-140. https://doi.org/10.1016/S0378-5173(97)00135-X

Szoka Jr, F., & Papahadjopoulos, D. (1978). Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation. Proceedings of the National Academy of Sciences of the United States of America, 75(9), 4194-4198. https://doi.org/10.1073/pnas.75.9.4194

Torchilin, V. P. (2005). Recent advances with liposomes as pharmaceutical carriers. Nature Reviews Drug Discovery, 4(2), 145-160. https://doi.org/10.1038/nrd1632

Van Eck, N. & Waltman, L. (2010). Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics, 84(2), 523-538. https://doi.org/10.1007/s11192-009-0146-3

Ventola, C. L. (2017). Progress in nanomedicine: Approved and investigational nanodrugs. P & T : A Peer-Reviewed Journal for Formulary Management, 42(12), 742-755. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720487/

Yadav, D., Sandeep, K., Pandey, D., Dutta, R. K. (2017). Liposomes for Drug Delivery. Journal of Biotechnology & Biomaterials, 7(4), 276. https://doi.org/10.4172/2155-952X.1000276

Yatvin, M. B., Weinstein, J. N., Dennis, W. H. & Blumenthal, R. (1978). Design of liposomes for enhanced local release of drugs by hyperthermia. Science (New York, N.Y.), 202(4374), 1290-1293. https://doi.org/10.1126/science.364652

Zhou, X., & Zhao, G. (2015). Global liposome research in the period of 1995-2014: A bibliometric analysis. Scientometrics, 105(1), 231-248. https://doi.org/10.1007/s11192-015-1659-6

International Journal of Information Science and Management (IJISM)

Liposomes, The Attractive Vehicles for Drug Delivery: A Scientometric Mapping of Web of Science Indexed Literature

References

References

Volume 21, Issue 4
October 2023
Pages 329-355

Liposomes, The Attractive Vehicles for Drug Delivery: A Scientometric Mapping of Web of Science Indexed Literature

References

References

Volume 21, Issue 4October 2023Pages 329-355

Volume 21, Issue 4
October 2023
Pages 329-355